Korean Polynucleotide Microneedling with DermaPen4® & Mesotherapy Dual Treatment
Our most advanced regenerative polynucleotide treatment, combining medical microneedling with targeted mesotherapy injections for enhanced skin rejuvenation.
This dual approach delivers Korean PDRN polynucleotides both throughout the skin and directly into areas requiring additional repair, helping to improve skin quality, elasticity, hydration and overall skin health from within.
Designed for clients seeking more intensive regeneration and collagen stimulation than microneedling alone.
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This treatment combines DermaPen4® microneedling with targeted polynucleotide mesotherapy injections.
By delivering polynucleotides through multiple methods, the treatment supports collagen production, tissue repair and cellular regeneration on a deeper level, helping to strengthen and rejuvenate compromised skin.
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Ageing skin
Fine lines and wrinkles
Loss of elasticity
Acne scarring
Dehydrated skin
Dull complexion
Skin recovery and repair
Advanced skin rejuvenation
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Whilst microneedling alone encourages collagen production, combining it with mesotherapy allows for a higher concentration of regenerative ingredients in targeted areas.
This makes it ideal for clients looking for a more intensive treatment programme focused on long-term skin health and regeneration.
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A course of 3-4 treatments is typically recommended.
Treatments are normally performed every 4 weeks, depending on your skin condition and goals.
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Every treatment begins with a detailed assessment of your skin concerns and goals.
Microneedling is performed throughout the treatment area, followed by targeted mesotherapy placement where additional support and regeneration are required.
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Redness and mild swelling are expected immediately after treatment.
The skin may remain pink for 24-48 hours, with occasional sensitivity or dryness for several days. Minor swelling at injection points may occur and generally settles quickly.
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Avoid retinol, exfoliating acids, anti-inflammatory medication and excessive sun exposure for several days before treatment.
Follow any personalised pre-treatment guidance provided during your consultation.
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Skin often appears more hydrated and radiant within days of treatment.
Collagen stimulation and tissue regeneration continue over several weeks, resulting in healthier, firmer and more resilient skin.
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At SÔMA SKIN, we combine advanced regenerative medicine with personalised treatment planning, ensuring every protocol is tailored to your skin's individual needs and long-term goals.
IS THIS TREATMENT RIGHT FOR ME?
If you're looking for maximum skin regeneration, improved skin quality and a more intensive approach to skin ageing, scarring or skin repair, this treatment may be ideal.